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FoxA2 Mouse anti-Human, Unlabeled, Clone: N17-280, BD

Catalog No. BDB561580 Shop All BD Biosciences Products
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BDB561580 0.1 mg
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Catalog No. BDB561580 Supplier BD Biosciences Supplier No. 561580

Description

Mouse Monoclonal Antibody

FoxA2, forkhead box A2, is a member of the forkhead class of DNA-binding proteins that regulates gene expression in the liver, pancreatic islets, adipocytes and some neural cells. This hepatocyte nuclear factor is a transcriptional activator for liver-specific genes such as alpha fetoprotein, albumin, tyrosine aminotransferase and transthyretin. FoxA2 is expressed in embryonic endoderm, the germ layer that gives rise to the digestive system, and contributes to the specification of the pancreas and the regulation of glucose homoeostasis. FoxA2 also has roles in neural development. Specifically, FoxA2 cooperates with related FoxA1 in the specification and differentiation of midbrain dopaminergic neurons in a dosage-dependent manner.

TRUSTED_SUSTAINABILITY

Specifications

Antigen FoxA2
Applications Western Blot
Classification Monoclonal
Clone N17-280
Concentration 0.5mg/mL
Conjugate Unconjugated
Description Forkhead box A2, HNF3B, HNF-3B, HNF-3β, hepatocyte nuclear factor 3β
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human FoxA2 Peptide
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human, Mouse
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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