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Granzyme B Mouse anti-Human, PE-CF594, Clone: GB11, BD

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Description

Mouse Monoclonal Antibody

Monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. Antibody was conjugated with Horizon™ PE-CF594 under optimum conditions, and unconjugated antibody and free PE-CF594 were removed. Granzyme B is stored in the granules of cytotoxic T lymphocytes and NK cells along with the pore-forming protein perforin. Granzyme B acts on specific substrates including caspase-3, -7, -9, and -10 which in turn give rise to enzymes that mediate apoptosis.

Host Species: Mouse
Clone: GB11
Isotype: IgG1, κ
Species Reactivity: Human
Immunogen: Human Granzyme B

  • Involved in the hydrolysis of extracellular matrix components
  • PE-CF594 can be excited by the blue (488nm), green (532nm) and yellow-green (561nm) lasers and can be detected with the same filter set as PE-Texas Red

Intracellular Staining, Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen Granzyme B
Applications Flow Cytometry
Classification Monoclonal
Clone GB11
Concentration 5μL
Conjugate PE-CF594
Description GZMB; Granzyme-2; CCPI; CGL1; CSPB; CTLA1; CTSGL1; GRB; HLP; SECT
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human Granzyme B
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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