HLA-DR Mouse anti-Human, Brilliant Violet 605, Clone: G46-6, BD

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
BDB562844	BD Biosciences 562844	25 Tests
BDB562845	BD Biosciences 562845	100 Tests

Description

The G46-6 monoclonal antibody specifically binds to HLA-DR, a major histocompatibility complex (MHC) class II antigen. HLA-DR antigens are encoded by genes within the Human Leukocyte Antigen (HLA) Complex located on chromosome 6. HLA-DR is a transmembrane heterodimeric glycoprotein composed of an α chain (36 kDa) and a β subunit (27 kDa) expressed primarily on antigen presenting cells: B cells, dendritic cells, monocytes, macrophages, and thymic epithelial cells. HLA-DR is also expressed on activated T cells. This molecule plays a major role in mediating cellular interactions during antigen presentation to CD4-positive T cells.

For optimal and reproducible results, BD Horizon Brilliant Stain Buffer should be used anytime two or more BD Horizon Brilliant dyes are used in the same experiment. Fluorescent dye interactions may cause staining artifacts which may affect data interpretation. The BD Horizon Brilliant Stain Buffer was designed to minimize these interactions. More information can be found in the Technical Data Sheet of the BD Horizon Brilliant Stain Buffer (Cat. No. 563794).

Specifications

• Antigen: HLA-DR
• Applications: Flow Cytometry
• Conjugate: Brilliant Violet 605
• Regulatory Status: RUO
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Clone: G46-6
• Classification: Monoclonal
• Host Species: Mouse
• Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
• Isotype: IgG2a κ
• Purification Method: Affinity Purified
• Description: MHC class II antigen; HLA class II histocompatibility antigen

For Research Use Only.