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Advanced ImmunoChemical, Inc. ANTI-HUMAN INSULIN MAB
Supplier: Advanced ImmunoChemical, Inc. 1I11 MG

Monoclonal antibodies / Metabolic Syndrome / Monoclonal mouse anti-human insulin. MAbs:C7C9, D4B8, 7F8, 3A6, 8E2, 7F5. Hybridoma clones have been derived from hybridization of X63-Ag8-653 myeloma cells with spleen cells of Balb/c mice immunized with purified human insulin.Specificity: Insulin, human; MAb C7C9 reacts with C-terminal pentapeptide of insulin β-chain. MAbs 7F8, D4B8, 3A6 and 8E2 react with different antigenic determinants. Kass for MAb 7F8 is 7.5 x 109M-1; Kass for MAb D4B8 is 1.5 x 108M-1; Kass for MAb 3A6 is 8.0 x 108M-1; Kass for MAb 8E2 is 6.0 x 108M-1; Kass for MAb C7C9 is 1.0 x 109M-1; Kass for MAb 7F5 is 1.0 x 109M-1. These antibodies cross-react with human proinsulin, bovine insulin (30%) and porcine insulin. No cross-reaction with free C-peptide. MAb isotypes: IgG1, kappa for all MAbs applications: Detection of insulin in two-site enzyme immunoassay.
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