IgD Mouse anti-Human, BB515, Clone: IA6-2, BD

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
BDB565244	BD Biosciences 565244	25 Tests
BDB565243	BD Biosciences 565243	100 Tests

Description

The IA6-2 monoclonal antibody specifically binds to the heavy chain of human Immunoglobulin D (IgD). IgD is a member of the immunoglobulin superfamily that exists in type 1-membrane (mIgD) and soluble glycoprotein forms. mIgD is expressed on mature naοve B cells (along with membrane IgM) and serves as a B-cell receptor for antigen (BCR). In response to antigen binding, the mIgD BCR, in association with other signaling molecules including CD79a and CD79b, can transduce activating or tolerizing signals intracellularly into B lymphocytes.

The antibody was conjugated to BD Horizon BB515 which was developed exclusively by BD Biosciences. With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (e.g. 530/30-nm filter). This dye provides a much brighter alternative to FITC with less spillover into the PE detector.

Specifications

• Antigen: IgD
• Applications: Flow Cytometry
• Conjugate: Brilliant Blue 515 (BB515)
• Regulatory Status: RUO
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide
• Isotype: IgG2a κ
• Purification Method: Affinity Purified
• Description: IGHD; Ig delta chain C region; Immunoglobulin heavy constant delta

• Clone: IA6-2
• Classification: Monoclonal
• Host Species: Mouse
• Target Species: Human
• Immunogen: Human IgD
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.