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AdipoGen anti-IL-1alpha (p18) (mouse), mAb (Teo-1)
SDP

Supplier:  AdipoGen AG20B0064C100

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anti-IL-1alpha (p18) (mouse), mAb (Teo-1), AdipoGen Life Sciences. Monoclonal Antibody. Recognizes mouse IL-1alpha p18 cleaved and full-length fragments. Isotype: Mouse IgG. Clone: Teo-1. Applications: ELISA, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism. IL-1alpha was reported to be more widely and constitutively expressed and has intracellular functions, but also acts locally in a membrane-bound form by activating IL-1R1. Additionally, passive release of IL-1alpha upon cell death can trigger a sterile inflammatory response to dying cells. The cleavage of IL-1alpha is not mediated by caspase-1 and is not required for binding to IL-1R1.

Catalog No. 50-101-5690


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