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IL-21 Mouse anti-Human, Unlabeled, Clone: J148-1134, BD

Catalog No. BDB558503 Shop All BD Biosciences Products
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BDB558503 0.5 mg
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Catalog No. BDB558503 Supplier BD Biosciences Supplier No. 558503
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Description

Mouse Monoclonal Antibody

The J148-1134 antibody reacts with interleukin-21 (IL-21), an ∽15kDa member of the type-I-cytokine family of proteins. IL-21 is expressed primarily by CD4+ T cells and has a broad range of immunoregulatory functions on B cells, CD8+ T cells, NK cells and dendritic cells. The effects of IL-21 include promotion of antibody production, NK cell differentiation, proliferation and differentiation of cells of monocyte and granulocytem lineages, costimulation of T cells and augmentation of antitumor activity of CD8+ T cells. It has been speculated that IL-21, through its varies positive and negative regulatory effects on cell-mediated and humoral immunity, may play a role in autoimmuninty, allergy, asthma and tumor regression.

ELISA

TRUSTED_SUSTAINABILITY

Specifications

Antigen IL-21
Applications ELISA
Classification Monoclonal
Clone J148-1134
Concentration 0.5mg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human IL-21 Recombinant Protein
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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