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IL5RA Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527900

Catalog No. PIPA527900


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Description

Description

PA5-27900 targets IL5 Receptor alpha in WB applications and shows reactivity with Human samples. The PA5-27900 immunogen is recombit fragment corresponding to a region within amino acids 1 and 339 of Human IL5 Receptor alpha. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.
Specifications

Specifications

IL5RA
Polyclonal
Unconjugated
IL5RA
Liquid
IL5RA
Recombit fragment corresponding to a region within amino acids 1 and 339 of Human IL5 Receptor alpha
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
1 mg/mL
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Q01344
CD125, CDw125, HSIL5R3, IL5R, CD125 antigen, IL-5 receptor subunit alpha, IL-5R subunit alpha, interleukin 5 receptor type 3, interleukin-5 receptor alpha chain, interleukin-5 receptor subunit alpha
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
3568
Documents
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