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Integrin b7 chain Rat anti-Mouse, FITC, Clone: M293, BD

Catalog No. BDB557497 Shop All BD Biosciences Products
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BDB557497 0.1 mg
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Catalog No. BDB557497 Supplier BD Biosciences Supplier No. 557497

Description

Rat Monoclonal Antibody

The M293 antibody reacts with the integrin β7 chain (also known as integrin βp), which is found in association with either of two α chains. α4β7 (LPAM-1) is expressed on most mature lymphocytes and on small subsets of thymic and bone marrow cells; it interacts with several ligands, including VCAM-1, fibronectin, and MAdCAM-1. αIELβ7 is found primarily on intestinal mucosal and intraepithelial lymphocytes (IEL), and it may be primarily involved in interactions between IEL and epithelia via recognition of E-cadherin. The epitope recognized by the mAb M293 has been mapped to the region between amino acids 387 and 542. The M293 antibody exhibits little or no activity in blocking β7 integrin-mediated adhesion.

Host Species: Rat
Clone: M293
Isotype: IgG2a, κ
Species Reactivity: Mouse
Immunogen: <special id='301'/>IEL<special id='302'/>7 integrin from the C57BL/10 mouse T-cell hybridoma MTC-1

Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen Integrin b7 chain
Applications Flow Cytometry
Classification Monoclonal
Clone M293
Concentration 0.5mg/mL
Conjugate FITC
Description Integrin βp
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Rat
Immunogen αIELβ7 integrin from the C57BL/10 mouse T-cell hybridoma MTC-1
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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For Research Use Only.

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