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Intersectin/ESE-1 Mouse, Unlabeled, Clone: 29, BD

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BDB611574 50 μg
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Catalog No. BDB611574 Supplier BD Biosciences Supplier No. 611574
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Description

Mouse Monoclonal Antibody

ESE-1 (epithelium-specific, EH domain and SH3 domain regulator of endocytosis) contains two N-terminal EH (Ep15 homology) domains, a central coiled-coil domain, and five C-terminal SH3 domains. ESE-1 is also known as the adaptor protein Intersectin. Intersectin constitutively associates with Eps15 to form a complex that is analogous to the yeast Pan1p-End3p complex, which is required for endocytosis and organization of the actin cytoskeleton. The EH, coiled-coil, and SH3 domains of intersectin bind epsin family proteins, SNAP25 and SNAP23, and dynamin, respectively. Thus, intersectin functions in complex with Eps15 to regulate endocytosis by linking components of the endocytic machinery.

Host Species: Mouse
Clone: 29
Isotype: IgG1
Species Reactivity: Rat
Immunogen: Mouse Ese-1 aa. 800-909
Formula Weight [Chemical]: 140/200kDa

Immunofluorescence, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen Intersectin/ESE-1
Applications Western Blot
Classification Monoclonal
Clone 29
Concentration 250μg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Mouse Ese-1 aa. 800-909
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Chicken, Mouse, Rat
Content And Storage Store undiluted at -20°C.
Isotype IgG1
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