IP3R-3 Mouse, Unlabeled, Clone: 2, BD

Catalog No.	Quantity
BDB610312	50 μg
BDB610313	150 μg

Catalog No. BDB610312 Supplier BD Biosciences Supplier No. 610312

Description

Mouse Monoclonal Antibody

Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for many hormones, growth factors, and neurotransmitters. IP3 causes the release of Ca²⁺ from intracellular stores by binding specific receptors that are coupled to Ca²⁺ channels. A number of studies have identified a family of at least four IP3 receptors (IP3R). The type III receptor (IP3R-3) has been isolated and characterized in human and rat. IP3 receptors are commonly localized in the endoplasmic reticulum, but have also been identified in the nucleus and the plasma membrane. Co-expression of different IP3 receptors is detected in most tissues and cell lines. Although these receptors appear to have a similar specificity for inositol phosphates, the different receptors have been reported to have different affinities for IP3 as follows: type II > type I > type III.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Specifications

• Antigen: IP3R-3
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 2
• Concentration: 250μg/mL
• Conjugate: Unconjugated
• Description: Inositol 1,4,5-triphosphate receptor type III
• Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
• Host Species: Mouse
• Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Quantity: 50 μg
• Regulatory Status: RUO
• Research Discipline: Cell Biology
• Primary or Secondary: Primary
• Target Species: Bovine, Canine, Human, Mouse, Rat
• Content And Storage: Store undiluted at -20°C.
• Isotype: IgG2a

For Research Use Only.