v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, Mouse, Clone: 3B10-2F2, Abnova™

Catalog No.	Quantity
89-014-138	100 μg

Catalog No. 89-014-138 Supplier Abnova Corporation Supplier No. H00003845M01

Description

Mouse monoclonal antibody raised against a full-length recombinant KRAS.

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq

Sequence: MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGHEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKKSKTKCVIM

Specifications

• Antigen: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
• Applications: ELISA, Immunofluorescence, Western Blot
• Classification: Monoclonal
• Clone: 3B10-2F2
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a full length recombinant KRAS.
• Formulation: PBS with no preservative; pH 7.4
• Gene: KRAS
• Gene Accession No.: BC013572
• Gene Alias: C-K-RAS/K-RAS2A/K-RAS2B/K-RAS4A/K-RAS4B/KI-RAS/KRAS1/KRAS2/NS3/RASK2
• Gene Symbols: KRAS
• Host Species: Mouse
• Immunogen: KRAS (AAH13572, 1 a.a. ∼ 188 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Research Discipline: Cell Cycle
• Primary or Secondary: Primary
• Gene ID (Entrez): 3845
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Isotype: IgG1 κ