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Langerin (CD207) Mouse anti-Human, PE, Clone: 2G3 (also known as AB5_8.2G3.6 ), BD

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Description

Mouse Monoclonal Antibody

The 2G3 monoclonal antibody specifically binds to Langerin which is also known as CD207 or C-type lectin domain family 4 member K (CLEC4K). CD207 is a 48 kDa type II transmembrane glycoprotein that belongs to the C-type lectin family. CD207 is selectively expressed by Langerhans cells, an immature dendritic cell type that is found in the epidermis and mucosal epithelia, and by some other dendritic cell subsets. CD207 is expressed on the cell surface membrane and by intracellular Birbeck granules whose formation depends on CD207. CD207 binds to certain surface carbohydrates that are expressed by microbes. It appears to play a role in the uptake of these microbes for subsequent processing and microbial antigen presentation to T cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen Langerin (CD207)
Applications Flow Cytometry
Classification Monoclonal
Clone 2G3 (also known as AB5_8.2G3.6 )
Conjugate PE
Description CLC4K; CLEC4K; C-type lectin domain family 4 member K
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human Langerin Recombinant Protein
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 λ
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