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MilliporeSigma™ anti-Ly-6G, PE-Cy7, Clone: 1A8,

Catalog No. p-5349714 Shop All MilliporeSigma Products
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MABF1424MI 25 μg
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Catalog No. MABF1424MI Supplier MilliporeSigma™ Supplier No. MABF1424
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Description

Rat Monoclonal Antibody

Specifically detects Ly-6G Clone: 1A8 in Mouse samples, and it is validated for Flow Cytometry

The 1A8 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils. In the mouse, the 1A8 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes. Note: for identification of Ly-C, an alternative antibody, clone RB6-8C5, has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151: 2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ly-6G
Applications Flow Cytometry
Classification Monoclonal
Clone 1A8
Conjugate PE-Cyanine7
Formulation Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Gene Accession No. P35461
Gene Symbols Ly6g
Host Species Rat
Immunogen Proprietary immunogen
Purification Method Purified by size-exclusion chromatography
Quantity 25 μg
Regulatory Status RUO
Research Discipline Inflammation, Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage 2°C to 8°C for one year from date of shipment protected from light; Do not freeze
Form Purified
Isotype IgG2a κ
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For Research Use Only

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