Mac-3 Rat anti-Mouse, Unlabeled, Clone: M3/84, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 553322

Catalog No. BDB553322

Description

The M3/84 antibody reacts with the 110kDa Mac-3 antigen expressed on mouse mononuclear phagocytes. Surface expression of the 92 to 110kDa glycoprotein antigen increases during differentiation of monocytes to activated peritoneal macrophages. The M3/84 mAb can detect CD107b antigen on tissue macrophages, thioglycollate-elicited peritoneal macrophages, and some myeloid cell lines, but not on lymphocytes or monocytes. In the bone marrow, very few cells display CD107b antigen on the surface, but a large proportion express cytoplasmic CD107b. The M3/84 antibody has also been reported to stain dendritic cells and endothelium in sections of thymus (both medulla and cortex), lymph nodes, spleen (white pulp), and gut-associated lymphoid tissue.

Specifications

• Antigen: Mac-3
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Mouse C57Bl/6 peritoneal exudate cells
• Quantity: 0.5 mg
• Research Discipline: Immunology
• Target Species: Mouse
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: M3/84
• Conjugate: Unconjugated
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

For Research Use Only.