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Mac-3 Rat anti-Mouse, Unlabeled, Clone: M3/84, BD

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Description

Rat Monoclonal Antibody

The M3/84 antibody reacts with the 110kDa Mac-3 antigen expressed on mouse mononuclear phagocytes. Surface expression of the 92 to 110kDa glycoprotein antigen increases during differentiation of monocytes to activated peritoneal macrophages. The M3/84 mAb can detect CD107b antigen on tissue macrophages, thioglycollate-elicited peritoneal macrophages, and some myeloid cell lines, but not on lymphocytes or monocytes. In the bone marrow, very few cells display CD107b antigen on the surface, but a large proportion express cytoplasmic CD107b. The M3/84 antibody has also been reported to stain dendritic cells and endothelium in sections of thymus (both medulla and cortex), lymph nodes, spleen (white pulp), and gut-associated lymphoid tissue.

TRUSTED_SUSTAINABILITY

Specifications

Antigen Mac-3
Applications Flow Cytometry
Classification Monoclonal
Clone M3/84
Concentration 31.25μg/mL
Conjugate Unconjugated
Description CD107b; Lamp2; LAMP-2; Lysosome-associated membrane glycoprotein 2; LGP-B
Formulation Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide.
Host Species Rat
Immunogen Mouse C57Bl/6 peritoneal exudate cells
Purification Method Affinity Purified
Quantity 1 mL
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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For Research Use Only.

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