Mac-3 Rat anti-Mouse, Unlabeled, Clone: M3/84, BD
Rat Monoclonal Antibody
Manufacturer: BD Biosciences 550292
The M3/84 antibody reacts with the 110kDa Mac-3 antigen expressed on mouse mononuclear phagocytes. Surface expression of the 92 to 110kDa glycoprotein antigen increases during differentiation of monocytes to activated peritoneal macrophages. The M3/84 mAb can detect CD107b antigen on tissue macrophages, thioglycollate-elicited peritoneal macrophages, and some myeloid cell lines, but not on lymphocytes or monocytes. In the bone marrow, very few cells display CD107b antigen on the surface, but a large proportion express cytoplasmic CD107b. The M3/84 antibody has also been reported to stain dendritic cells and endothelium in sections of thymus (both medulla and cortex), lymph nodes, spleen (white pulp), and gut-associated lymphoid tissue.
|CD107b; Lamp2; LAMP-2; Lysosome-associated membrane glycoprotein 2; LGP-B|
|Store undiluted at 4°C|
|Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide.|
|Mouse C57Bl/6 peritoneal exudate cells|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok
For Research Use Only.