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Mac-3 Rat anti-Mouse, Unlabeled, Clone: M3/84, BD

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 550292

Catalog No. BDB550292


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Description

Description

The M3/84 antibody reacts with the 110kDa Mac-3 antigen expressed on mouse mononuclear phagocytes. Surface expression of the 92 to 110kDa glycoprotein antigen increases during differentiation of monocytes to activated peritoneal macrophages. The M3/84 mAb can detect CD107b antigen on tissue macrophages, thioglycollate-elicited peritoneal macrophages, and some myeloid cell lines, but not on lymphocytes or monocytes. In the bone marrow, very few cells display CD107b antigen on the surface, but a large proportion express cytoplasmic CD107b. The M3/84 antibody has also been reported to stain dendritic cells and endothelium in sections of thymus (both medulla and cortex), lymph nodes, spleen (white pulp), and gut-associated lymphoid tissue.

Specifications

Specifications

Mac-3
Monoclonal
31.25μg/mL
CD107b; Lamp2; LAMP-2; Lysosome-associated membrane glycoprotein 2; LGP-B
Rat
Affinity Purified
RUO
Primary
Store undiluted at 4°C
Flow Cytometry
M3/84
Unconjugated
Aqueous buffered solution containing BSA, goat serum, and ≤0.09% sodium azide.
Mouse C57Bl/6 peritoneal exudate cells
1 mL
Immunology
Mouse
IgG1 κ
SDS
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