MAEL Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520923
A suggested positive control is Hela cell lysate. PA5-20923 can be used with blocking peptide PEP-1037.The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5’-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.
|A 16 amino acid peptide near the carboxy terminus of human Maelstrom.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 0.02% sodium azide|
|CT128, RP11-102C16.1; cancer/testis antigen 128; protein maelstrom homolog|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|364039, 84944, 98558|
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