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MAEL Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520923

Catalog No. PIPA520923


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Description

Description

A suggested positive control is Hela cell lysate. PA5-20923 can be used with blocking peptide PEP-1037.

The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5’-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.
Specifications

Specifications

MAEL
Polyclonal
Unconjugated
MAEL
Liquid
MAEL
A 16 amino acid peptide near the carboxy terminus of human Maelstrom.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q96JY0, Q8BVN9
CT128, RP11-102C16.1; cancer/testis antigen 128; protein maelstrom homolog
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
364039, 84944, 98558
Documents
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