MilliporeSigma™ anti-MHC class II (I-A/I-E), APC, Clone: M5/114.15.2,

Rat Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
MABF805MI	MilliporeSigma™ MABF805	25 μg
MABF806MI	MilliporeSigma™ MABF806	100 μg

Description

Specifically detects MHC class II (I-A/I-E) Clone: M5/114.15.2 in Mouse samples, and it is validated for Flow Cytometry

The M5/114.15.2 antibody reacts with mouse MHC Class II alloantigens I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek, as well as being cross-reactive with mouse cells of H-2p and H-2r haplotype. MHC Class II is widely expressed by mouse immune cells bearing these alloantigens, including T and B cells, monocytes, macrophages, and dendritic cells. The antibody does not react with the following alloantigens: I-Af, I-Ak, I-As, or NOD H-2g7.The M5/114.15.2 antibody may be used for analysis of mouse cells expressing MHC Class II alloantigens as described. Please note that the M5/114.15.2 clone may also be referred to as M5/114 in the literature.

Specifications

• Antigen: MHC class II (I-A/I-E)
• Applications: Flow Cytometry
• Conjugate: APC
• Host Species: Rat
• Research Discipline: Inflammation, Immunology
• Formulation: Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
• Gene Symbols: CD74, Ii
• Isotype: IgG2b κ
• Purification Method: Purified by size-exclusion chromatography

• Clone: M5/114.15.2
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Mouse
• Gene Accession No.: P04441
• Immunogen: Proprietary immunogen
• Primary or Secondary: Primary
• Content And Storage: 2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze

For Research Use Only