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MST1/MST2 Mouse anti-Human, Clone: 1E9, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA520043

Catalog No. PIMA520043


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Description

Description

Peptide Sequence: MEQPPAPKSK LKKLSEDSLT KQPEEVFDVL EKLGEGSYGS VFKAIHKESG QVVAIKQVPV ESDLQEIIKE ISIMQQCDSP YVVKYYGSYF KNTDLWIVME YCGAGSVSDI IRLRNKTLIE DEIATILKST LKGLEYLHFM RKIHRDIKAG NILLNTEGHA KLADFGVAGQ LTDTMAKRNT VIGTPFWMAP EVIQEIGYNC VADIWSLGIT SIEMAEGKPP YADIHPMRAI FMIPTNPPPT FRKPELWSDD FTDFVKKCLV KNPEQRATAT QLLQHPFIKN AKPVSILRDL ITEAMEIKAK RHEEQQRELE EEEENSDEDE LDSHTMVKTS VESVGTMRAT STMSEGAQTM IEHNSTMLES DLGTMVINSE DEEEEDGTMK RNATSPQVQR PSFMDYFDKQ DFKNKSHENC NQNMHEPFPM SKNVFPDNWK VPQDGDFDFL KNLSLEELQM RLKALDPMME REIEELRQRY TAKRQPILDA MDAKKRRQQN F

Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast  ft.sterile 20 ft. (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand (MIM 134638) (Taylor et al., 1996 [PubMed 8816758]; Lee et al., 2001 [PubMed 11278283]).
Specifications

Specifications

MST1/MST2
Monoclonal
0.2 mg/mL
PBS with no preservative; pH 7.4
Q13043, Q13188
KRS1, MST2, MST-2, STE20-like kinase MST2, mammalian STE20-like protein kinase 2, serine/threonine kinase 3 (STE20 homolog, yeast), serine/threonine kinase 3 (Ste20, yeast homolog), serine/threonine-protein kinase 3, serine/threonine-protein kinase Krs-1
Mouse
IgG1, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
6788, 6789
ELISA, Immunocytochemistry, Immunofluorescence
1E9
Unconjugated
STK3
Liquid
STK3, STK4
STK3 (AAH10640, 1 a.a. ∽ 491 a.a) full-length recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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