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mTOR Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA513263

Catalog No. PIPA513263


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Description

Description

This antibody is predicted to react with mouse and rat based on sequence homology.

FRAP1 belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. FRAP1 is a part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.
Specifications

Specifications

mTOR
Polyclonal
Unconjugated
MTOR
Liquid
MTOR
KLH conjugated synthetic peptide between 2459-2488 amino acids from human mTOR (FRAP1)
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.09% sodium azide
P42345
FK506-binding protein 12-rapamycin complex-associated protein 1; Rapamycin target protein; RAPT1; Mammalian target of rapamycin; mTOR, mTORC1
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
2475
Documents
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