MYZAP Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA521116
A suggested positive control is rat kidney tissue lysate. PA5-21116 can be used with blocking peptide PEP-1230.MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.
|An 18 amino acid peptide near the carboxy terminus of human MYOZAP.|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot|
|PBS with 0.02% sodium azide|
|P0CAP1, Q3UIJ9, Q5EB94|
|GRINL1A, Gcom2, MYZAP-POLR2M, gcom; GRINL1A combined protein; GRINL1A combined protein Gcom12; GRINL1A complex locus protein 1; MYZAP-POLR2M protein; MYZAP-POLR2M readthrough; NMDAR1 subunit-interacting protein; glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A combined protein|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|100820829, 102371, 363091|
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