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Nanog Mouse anti-Mouse, Alexa Fluor 488, Clone: M55-312, BD

Catalog No. BDB560278 Shop All BD Biosciences Products
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Catalog No. BDB560278 Supplier BD Biosciences Supplier No. 560278
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Description

Mouse Monoclonal Antibody

The M55-312 monoclonal antibody reacts with mouse Nanog (named for Tir Na Nog, the land of the ever-young of Celtic mythology), which is a homeobox transcription factor required for the maintenance of the undifferentiated state of pluripotent stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF (Leukemia Inhibitory Factor) and BMP (Bone Morphogenic Protein). When Nanog expression is down-regulated, cell differentiation can proceed. Proteins that regulate Nanog expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.

TRUSTED_SUSTAINABILITY

Specifications

Antigen Nanog
Applications Flow Cytometry
Classification Monoclonal
Clone M55-312
Conjugate Alexa Fluor 488
Formulation Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Mouse Nanog Recombinant Protein
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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