Nanog Mouse anti-Mouse, Unlabeled, Clone: M55-312, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 560259

Catalog No. BDB560259

Description

The M55-312 monoclonal antibody reacts with mouse Nanog (named for Tir Na Nog, the land of the ever-young of Celtic mythology), which is a homeobox transcription factor required for the maintenance of the undifferentiated state of pluripotent stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF (Leukemia Inhibitory Factor) and BMP (Bone Morphogenic Protein). When Nanog expression is down-regulated, cell differentiation can proceed. Proteins that regulate Nanog expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.

Host Species: Mouse
Clone: M55-312
Isotype: IgG1 κ
Species Reactivity: Mouse
Immunogen: Mouse Nanog Recombinant Protein

Bioimaging, Western Blotting

Specifications

• Antigen: Nanog
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Mouse Nanog Recombinant Protein
• Quantity: 0.1 mg
• Research Discipline: Cell Biology
• Target Species: Mouse
• Isotype: IgG1 κ

• Applications: In vitro Assay, Western Blot
• Clone: M55-312
• Conjugate: Unconjugated
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C