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Nanog Mouse anti-Mouse, Unlabeled, Clone: M55-312, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 560259
Description
The M55-312 monoclonal antibody reacts with mouse Nanog (named for Tir Na Nog, the land of the ever-young of Celtic mythology), which is a homeobox transcription factor required for the maintenance of the undifferentiated state of pluripotent stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF (Leukemia Inhibitory Factor) and BMP (Bone Morphogenic Protein). When Nanog expression is down-regulated, cell differentiation can proceed. Proteins that regulate Nanog expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.
Host Species: Mouse
Clone: M55-312
Isotype: IgG1 κ
Species Reactivity: Mouse
Immunogen: Mouse Nanog Recombinant Protein
Bioimaging, Western Blotting

Specifications
Nanog | |
Monoclonal | |
0.5mg/mL | |
Aqueous buffered solution containing ≤0.09% sodium azide. | |
Mouse Nanog Recombinant Protein | |
0.1 mg | |
Cell Biology | |
Mouse | |
IgG1 κ |
In vitro Assay, Western Blot | |
M55-312 | |
Unconjugated | |
Mouse | |
Affinity Purified | |
RUO | |
Primary | |
Store undiluted at 4°C |
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