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anti-NFKB1 Matched Antibody Pair, Abnova

Catalog No. 89017313 Shop All Abnova Corporation Products
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Catalog No. 89-017-313 Supplier Abnova Corporation Supplier No. H00004790AP21
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Includes

Rabbit MaxPab™ affinity purified polyclonal anti-NFKB1 (100μg); Mouse purified polyclonal anti-NFKB1 (20μg); Sufficient for at least 3-5 x 96 well plates using recommended protocols.

This gene encodes a 105kDa protein which can undergo cotranslational processing by the 26S proteasome to produce a 50kDa protein. The 105kDa protein is a Rel protein-specific transcription inhibitor and the 50kDa protein is a DNA binding subunit of the NF-κ-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.

ELISA

Specifications

Antigen NFKB1
Applications ELISA
Classification Monoclonal/Polyclonal
Conjugate Unconjugated
Description This antibody pair set comes with matched antibody pair to detect and quantify protein level of human NFKB1.
Gene NFKB1
Gene Alias DKFZp686C01211/EBP-1/KBF1/MGC54151/NF-kappa-B/NFKB-p105/NFKB-p50/p105/p50
Gene Symbols NFKB1
Host Species Mouse, Rabbit
Purification Method Affinity Purified
Quantity 1 Set
Regulatory Status RUO
Research Discipline Apoptosis
Primary or Secondary Primary
Gene ID (Entrez) 4790
Includes Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-NFKB1 (100 μg) 2. Detection antibody: mouse purified polyclonal anti-NFKB1 (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
Target Species Human
Content And Storage Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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