anti-NFKB1 Matched Antibody Pair, Abnova

Supplier:  Abnova Corporation H00004790AP21

Catalog No. 89-017-313

Includes: Rabbit MaxPab™ affinity purified polyclonal anti-NFKB1 (100μg); Mouse purified polyclonal anti-NFKB1 (20μg); Sufficient for at least 3-5 x 96 well plates using recommended protocols.

Description

This gene encodes a 105kDa protein which can undergo cotranslational processing by the 26S proteasome to produce a 50kDa protein. The 105kDa protein is a Rel protein-specific transcription inhibitor and the 50kDa protein is a DNA binding subunit of the NF-κ-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.

ELISA

Specifications

• Antigen: NFKB1
• Classification: Monoclonal/Polyclonal
• Description: This antibody pair set comes with matched antibody pair to detect and quantify protein level of human NFKB1.
• Gene Alias: DKFZp686C01211/EBP-1/KBF1/MGC54151/NF-kappa-B/NFKB-p105/NFKB-p50/p105/p50
• Host Species: Mouse, Rabbit
• Quantity: 1 Set
• Research Discipline: Apoptosis
• Gene ID (Entrez): 4790
• Target Species: Human

• Applications: ELISA
• Conjugate: Unconjugated
• Gene: NFKB1
• Gene Symbols: NFKB1
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Includes: Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-NFKB1 (100 μg) 2. Detection antibody: mouse purified polyclonal anti-NFKB1 (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
• Content And Storage: Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.