anti-NFKBIB Matched Antibody Pair, Abnova

Supplier:  Abnova Corporation H00004793AP11

Catalog No. 89-017-314

Includes: Rabbit MaxPab™ affinity purified polyclonal anti-NFKBIB (100μg); Mouse monoclonal anti-NFKBIB, IgG2aκ (20μg); Sufficient for at least 3-5 x 96 well plates using recommended protocols.

Description

NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-κ-B proteins (NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-κ-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-κ-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-κ-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at κ-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).

ELISA

Specifications

• Antigen: NFKBIB
• Classification: Monoclonal/Polyclonal
• Description: This antibody pair set comes with matched antibody pair to detect and quantify protein level of human NFKBIB.
• Gene Alias: IKBB/TRIP9
• Host Species: Mouse, Rabbit
• Quantity: 1 Set
• Research Discipline: Transcription Regulation
• Gene ID (Entrez): 4793
• Target Species: Human
• Isotype: IgG2a

• Applications: ELISA
• Conjugate: Unconjugated
• Gene: NFKBIB
• Gene Symbols: NFKBIB
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Includes: Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-NFKBIB (100 μg) 2. Detection antibody: mouse monoclonal anti-NFKBIB, IgG2a Kappa (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
• Content And Storage: Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.