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Nkx6.1 Mouse, Alexa Fluor 647, Clone: R11-560, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 563338

Catalog No. BDB563338


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Description

Description

The R11-560 monoclonal antibody specifically binds to human and mouse homeobox protein Nkx6.1. The transcription factor Nkx6.1 plays a role in pancreatic islet beta cell development through the regulation of HNF1a and insulin genes. Nkx6.1 is considered to be a highly specific transcription factor marking pancreatic beta islet cells, where it is expressed in both developing and mature cells. In addition, Nkx6.1 functions as a transcriptional repressor induced by the Sonic Hedgehog (Shh) signaling pathway in fate determination of several neuronal cell types. During antibody development, the purified R11-560 monoclonal antibody was found to detect Nkx6.1 by western blot and indirect immunofluorescent staining followed by flow cytometric analysis or imaging analysis.

Specifications

Specifications

Nkx6.1
R11-560
Nkx6.1, NKX6-1, NKX6A, Nkx6-1, Nkx6.1, Nkx6a
Affinity Purified
Human Nkx6.1 Recombinant Protein
50 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
Alexa Fluor 647
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Murine
IgG1, κ
RUO
Primary
Human, Murine
Documents
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