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Nkx6.1 Mouse, Alexa Fluor 647, Clone: R11-560, BD

Catalog No. BDB563338 Shop All BD Biosciences Products
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BDB563338 50 Tests
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Catalog No. BDB563338 Supplier BD Biosciences Supplier No. 563338
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Description

Mouse Monoclonal Antibody

The R11-560 monoclonal antibody specifically binds to human and mouse homeobox protein Nkx6.1. The transcription factor Nkx6.1 plays a role in pancreatic islet beta cell development through the regulation of HNF1a and insulin genes. Nkx6.1 is considered to be a highly specific transcription factor marking pancreatic beta islet cells, where it is expressed in both developing and mature cells. In addition, Nkx6.1 functions as a transcriptional repressor induced by the Sonic Hedgehog (Shh) signaling pathway in fate determination of several neuronal cell types. During antibody development, the purified R11-560 monoclonal antibody was found to detect Nkx6.1 by western blot and indirect immunofluorescent staining followed by flow cytometric analysis or imaging analysis.

TRUSTED_SUSTAINABILITY

Specifications

Antigen Nkx6.1
Applications Flow Cytometry
Classification Monoclonal
Clone R11-560
Conjugate Alexa Fluor 647
Description Nkx6.1, NKX6-1, NKX6A, Nkx6-1, Nkx6.1, Nkx6a
Formulation Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human Nkx6.1 Recombinant Protein
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human, Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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