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Nkx6.1 Mouse, PE, Clone: R11-560, BD

Catalog No. BDB563023 Shop All BD Biosciences Products
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Catalog No. BDB563023 Supplier BD Biosciences Supplier No. 563023
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Description

Mouse Monoclonal Antibody

The R11-560 monoclonal antibody specifically binds to human and mouse homeobox protein Nkx6.1. The transcription factor Nkx6.1 plays a role in pancreatic islet beta cell development through the regulation of HNF1a and insulin genes. Nkx6.1 is considered to be a highly specific transcription factor marking pancreatic beta islet cells, where it is expressed in both developing and mature cells. In addition, Nkx6.1 functions as a transcriptional repressor induced by the Sonic Hedgehog (Shh) signaling pathway in fate determination of several neuronal cell types. During antibody development, the purified R11-560 monoclonal
antibody was found to detect Nkx6.1 by western blot and indirect immunofluorescent staining followed by flow cytometric analysis or imaging analysis.

Host Species: Mouse
Clone: R11-560
Isotype: IgG1, κ
Species Reactivity: Hu, Ms
Immunogen: Human Nkx6.1 Recombinant Protein

Flow Cytometry, Intracellular Staining

TRUSTED_SUSTAINABILITY

Specifications

Antigen Nkx6.1
Applications Flow Cytometry
Classification Monoclonal
Clone R11-560
Conjugate PE
Description Nkx6.1, NKX6-1, NKX6A, Nkx6-1, Nkx6.1, Nkx6a
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human Nkx6.1 Recombinant Protein
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human, Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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