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Description
This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq
Specifications
Specifications
| Antigen | NOD2 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Rabbit polyclonal antibody raised against a full-length human NOD2 protein. |
| Formulation | PBS with no preservative; pH 7.4 |
| Gene | NOD2 |
| Gene Accession No. | BC156571.1 |
| Gene Alias | ACUG/BLAU/CARD15/CD/CLR16.3/IBD1/NLRC2/NOD2B/PSORAS1 |
| Gene Symbols | NOD2 |
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