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Invitrogen™ OGDH Polyclonal Antibody
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Catalog No. PIPA528195
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100 μL
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PIPA528195 100 μL
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Catalog No. PIPA528195 Supplier Invitrogen™ Supplier No. PA528195
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, HeLa, HepG2, Huh-7, Mouse brain. Predicted reactivity: Mouse (93%), Rat (93%), Xenopus laevis (84%), Chicken (87%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitocondrial matrix and uses thiamine pyrophosphate as a cofactor. A congential deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen OGDH
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene OGDH
Gene Accession No. Q02218, Q60597
Gene Alias 2210403E04Rik; 2210412K19Rik; 2-oxoglutarate dehydrogenase complex component E1; 2-oxoglutarate dehydrogenase E1 component, mitochondrial; 2-oxoglutarate dehydrogenase, mitochondrial; AA409584; AKGDH; Alpha-ketoglutarate dehydrogenase; d1401; E1k; Kiaa4192; mKIAA4192; OGDC; OGDC-E1; Ogdh; Ogdhl; oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide); oxoglutarate decarboxylase; oxoglutarate dehydrogenase; oxoglutarate dehydrogenase (lipoamide); oxoglutarate dehydrogenase (succinyl-transferring); testicular tissue protein Li 131
Gene Symbols OGDH
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human OGDH. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18293, 4967
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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