OGDH Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA528195
PA5-28195 targets OGDH in IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples. The PA5-28195 immunogen is recombit fragment corresponding to a region within amino acids 705 and 1000 of Human OGDH. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitocondrial matrix and uses thiamine pyrophosphate as a cofactor. A congential deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.
|Recombit fragment corresponding to a region within amino acids 705 and 1000 of Human OGDH|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 20% glycerol and 0.025% Proclin 300; pH 7|
|AKGDH, E1k, OGDC, 2-oxoglutarate dehydrogenase complex component E1, 2-oxoglutarate dehydrogenase, mitochondrial, OGDC-E1, oxoglutarate decarboxylase, oxoglutarate dehydrogenase (succinyl-transferring)|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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