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Description
Pax-6 is a member of the paired box (pax) gene family whose protein products are transcription factors involved in development. Pax family members share a highly conserved DNA binding domain that contains six alpha helices (paired domain) and a homeo box domain. Pax-6 has important roles in the development of the eye, nose, central nervous system, and pancreas. Defects in Pax-6 are responsible for various eye malformations including aniridia and Peters anomaly.
The O18-1330 monoclonal antibody reacts with human Pax-6. Because the Pax-6 protein sequence is highly conserved among vertebrate species, cross-reactivity with other species is possible.
Specifications
Specifications
| Antigen | Pax-6 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | O18-1330 |
| Conjugate | PE |
| Description | Oculorhombin, Aniridia type II protein, PAX6, AN2 |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Human Pax-6 aa 406-422 Peptide |
| Purification Method | Affinity Purified |
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