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PDX-1 Mouse, Alexa Fluor 488, Clone: 658A5, BD

Catalog No. BDB562274 Shop All BD Biosciences Products
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BDB562274 50 Tests
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Catalog No. BDB562274 Supplier BD Biosciences Supplier No. 562274
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Description

Mouse Monoclonal Antibody

The 658A5 monoclonal antibody binds PDX-1 or Pancreas/Duodenum Homeobox Protein-1 encoded by the PDX1 or IPF1 (Insulin Promoter Factor 1) gene. PDX-1 is a key regulator of pancreatic development and adult beta-cell function. Loss of PDX1 gene function in mice and humans results in pancreatic agenesis. PDX-1 is also involved in endocrine precursor cell development by binding the DNA-binding transcription factor Neurogenin-3. PDX-1-positive cells have been obtained by the directed differentiation of human embryonic stem cells through a definitive endoderm lineage.

TRUSTED_SUSTAINABILITY

Specifications

Antigen PDX-1
Applications Flow Cytometry
Classification Monoclonal
Clone 658A5
Conjugate Alexa Fluor 488
Description PDX1, GSF, IPF-1, IPF1, IUF-1, IDX-1, STF-1
Formulation Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human PDX-1 Recombinant Protein
Purification Method Affinity Purified
Quantity 50 Tests
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human, Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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