PDX-1 Mouse, PE, Clone: 658A5, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 562161

Catalog No. BDB562161

Description

The 658A5 monoclonal antibody binds PDX-1 or Pancreas/Duodenum Homeobox Protein-1 encoded by the PDX1 or IPF1 (Insulin Promoter Factor 1) gene. PDX-1 is a key regulator of pancreatic development and adult beta-cell function. Loss of PDX1 gene function in mice and humans results in pancreatic agenesis. PDX-1 is also involved in endocrine precursor cell development by binding the DNA-binding transcription factor Neurogenin-3. PDX-1-positive cells have been obtained by the directed differentiation of human embryonic stem cells through a definitive endoderm lineage.

Specifications

• Antigen: PDX-1
• Classification: Monoclonal
• Conjugate: PE
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Immunogen: Human PDX-1 Recombinant Protein
• Quantity: 50 Tests
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: 658A5
• Description: PDX1, GSF, IPF-1, IPF1, IUF-1, IDX-1, STF-1
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human, Mouse
• Isotype: IgG1 κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov