anti-RAD51 Matched Antibody Pair, Ab-1, Abnova

Supplier:  Abnova Corporation H00005888AP11

Catalog No. 89-017-336

Includes: Rabbit MaxPab™ affinity purified polyclonal anti-RAD51 (100μg); Mouse monoclonal anti-RAD51, IgG1κ (20μg); Sufficient for at least 3-5 x 96 well plates using recommended protocols.

Description

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.

ELISA

Specifications

• Antigen: RAD51
• Classification: Monoclonal/Polyclonal
• Description: This antibody pair set comes with matched antibody pair to detect and quantify protein level of human RAD51.
• Gene Alias: BRCC5/HRAD51/HsRad51/HsT16930/RAD51A/RECA
• Host Species: Mouse, Rabbit
• Quantity: 1 Set
• Primary or Secondary: Primary
• Includes: Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-RAD51 (100 μg) 2. Detection antibody: mouse monoclonal anti-RAD51, IgG1 Kappa (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
• Content And Storage: Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.

• Applications: ELISA
• Conjugate: Unconjugated
• Gene: RAD51
• Gene Symbols: RAD51
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 5888
• Target Species: Human
• Isotype: IgG1