Smallpox Virus B5R Mouse anti-Virus, Clone: 1J2F3, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA141212

Catalog No. 01-676-594

Description

This antibody is predicted to react with Bovinepox virus, Ectromelia virus, Monkeypox virus, Rabbitpox virus, and vaccinia virus.

Vaccinia virus, a member of Poxviridae family, is a dsDNA enveloped virus. It consists of 4 types of virion stages among which extracellular enveloped virus (EEV) is critical for cell-to-cell and long range viral infection. B5R is an EEV-specific Type I membrane glycoprotein essential for EEV formation. It consists of a large ectodomain containing regions similar to SCR domains of complement regulatory proteins followed by a transmembrane region and a cytoplasmic tail. B5R is essential for efficient wrapping of IMV, actin tail formation, normal plaque size, virus virulence, incorporation of the protein into EEV and for EEV formation.

Specifications

• Antigen: Smallpox Virus B5R
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.05% BSA and 0.05% sodium azide
• Host Species: Mouse
• Isotype: IgG1, kappa
• Quantity: 100 μg
• Storage Requirements: -20° C, Avoid Freeze/Thaw Cycles
• Primary or Secondary: Primary
• Target Species: Virus

• Applications: Western Blot
• Clone: 1J2F3
• Conjugate: Unconjugated
• Format: Liquid
• Immunogen: B5R protein.
• Purification Method: Protein G
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Monoclonal