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Invitrogen™ Smallpox Virus B5R Monoclonal Antibody (1J2F3)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA141212
Description
This antibody is predicted to react with Bovinepox virus, Ectromelia virus, Monkeypox virus, Rabbitpox virus, and vaccinia virus.
B5R is an EEV-specific Type I membrane glycoprotein essential for EEV formation. Vaccinia virus, a member of Poxviridae family, is a dsDNA enveloped virus. It consists of 4 types of virion stages among which extracellular enveloped virus (EEV) is critical for cell-to-cell and long range viral infection. Some cellular antigens are associated with EEV and these vary with the cell type used to grow the virus. B5R consists of a large ectodomain containing regions similar to SCR domains of complement regulatory proteins followed by a transmembrane region and a cytoplasmic tail. B5R is essential for efficient wrapping of IMV, actin tail formation, normal plaque size, virus virulence, and for EEV formation.
Specifications
Smallpox Virus B5R | |
Monoclonal | |
1.0 mg/mL | |
PBS with 0.05% sodium azide | |
Amino acids 33-47 (IQEYNLIRTYKKVDK) of the B5R protein. | |
100 μg | |
Primary | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Western Blot | |
1J2F3 | |
Unconjugated | |
Mouse | |
Protein G | |
RUO | |
Virus | |
Antibody | |
IgG1 κ |
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