Invitrogen™ Smallpox Virus B5R Monoclonal Antibody (1J2F3)

Catalog No.	Quantity
01-676-594	100 μg

Catalog No. 01-676-594 Supplier Invitrogen™ Supplier No. MA141212

Description

Mouse Monoclonal Antibody

This antibody is predicted to react with Bovinepox virus, Ectromelia virus, Monkeypox virus, Rabbitpox virus, and vaccinia virus. Immunogen sequence: IQEYNLIRTY KKVDK.

B5R is an EEV-specific Type I membrane glycoprotein essential for EEV formation. Vaccinia virus, a member of Poxviridae family, is a dsDNA enveloped virus. It consists of 4 types of virion stages among which extracellular enveloped virus (EEV) is critical for cell-to-cell and long range viral infection. Some cellular antigens are associated with EEV and these vary with the cell type used to grow the virus. B5R consists of a large ectodomain containing regions similar to SCR domains of complement regulatory proteins followed by a transmembrane region and a cytoplasmic tail. B5R is essential for efficient wrapping of IMV, actin tail formation, normal plaque size, virus virulence, and for EEV formation.

Specifications

• Antigen: Smallpox Virus B5R
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 1J2F3
• Concentration: 1.0 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% sodium azide
• Host Species: Mouse
• Immunogen: Amino acids 33-47 of the B5R protein.
• Purification Method: Protein G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Virus
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 κ