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Description
The monoclonal antibody O30-678 recognizes the Sox2 transcription factor. Sox2[SRY (sex determining region Y)-box 2] is a member of theSRY-related HMG-box (SOX) family of transcription factors. Sox2 is required for the maintenance of the undifferentiated state of pluripotent stem cells. Complexes of Sox2 with the homeobox transcription factors Oct3/4 and/or Nanog bind to the promoters of a network of genes that are involved in the maintenance of pluripotency and self renewal in stem cells. Sox2 is also a marker of neural stem cells during embryonic development and in the adult brain. The O30-678 antibody recognizes both human and mouse Sox2 proteins.
Specifications
Specifications
| Antigen | Sox2 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | O30-678 |
| Conjugate | PerCP-Cyanine5.5 |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Human Sox2 Recombinant Protein |
| Purification Method | Affinity Purified |
| Quantity | 50 Tests |
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