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Description
The monoclonal antibody 245610 recognizes the Sox2 transcription factor. Sox2 (SRY (sex determining region Y)-box 2) is a member of the SRY-related HMG-box (SOX) family of transcription factors. Sox2 is required for the maintenance of the undifferentiated state of pluripotent stem cells. Complexes of Sox2 with the homeobox transcription factors Oct3/4 and/or Nanog bind to the promoters of a network of genes that are involved in the maintenance of pluripotency and self renewal in stem cells. The 245610 antibody recognizes both human and mouse proteins. Sox2 is also a marker of neural stem cells during embryonic development and in the adult brain.
Host Species: Mouse
Clone: 245610
Isotype: IgG2a
Species Reactivity: Human
Immunogen: Human SOX2 Recombinant Protein
Intracellular Staining
Specifications
Specifications
| Antigen | Sox2 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 245610 |
| Conjugate | PE |
| Description | ANOP3, MCOPS3, MGC2413 |
| Formulation | Aqueous buffered solution containing BSA and ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Human SOX2 Recombinant Protein |
| Purification Method | Affinity Purified |
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