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MilliporeSigma™ anti-SV40 T Antigen Clone: PAb416,

Catalog No. DP02200UG Shop All MilliporeSigma Products
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Quantity:
200 μg
Conjugate:
Unconjugated
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Catalog No. Quantity Conjugate
DP02200UG 200 μg Unconjugated
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Catalog No. DP02200UG Supplier MilliporeSigma™ Supplier No. DP02200UG
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Description

Mouse Monoclonal Antibody

Specifically detects SV40 T Antigen Clone: PAb416 in samples, and it is validated for Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation

SV40 T Ag (Ab-2) is a mouse monoclonal antibody with specificity for antigenic determinants unique to the SV40 large T antigen and non-reactive with SV40 small T antigen. Both antigens are encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular transforming protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the p105 product of the retinoblastoma susceptibility gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SV40 T Antigen
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Monoclonal
Clone PAb416
Conjugate Unconjugated
Formulation In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
Host Species Mouse
Immunogen purified SV40 large T-antigen
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity Recognizes ∽94kDa SV40 large T antigen in SV80 and SV-T2 cells.
Content And Storage 2°C to 8°C
Form Purified
Isotype IgG2a
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For Research Use Only

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