MilliporeSigma™ anti-SV40 T Antigen Clone: PAb416,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ DP02200UG

Catalog No. DP02200UG

Description

Specifically detects SV40 T Antigen Clone: PAb416 in samples, and it is validated for Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation

SV40 T Ag (Ab-2) is a mouse monoclonal antibody with specificity for antigenic determinants unique to the SV40 large T antigen and non-reactive with SV40 small T antigen. Both antigens are encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular transforming protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the p105 product of the retinoblastoma susceptibility gene.

Specifications

• Antigen: SV40 T Antigen
• Classification: Monoclonal
• Conjugate: Unconjugated
• Host Species: Mouse
• Quantity: 200 μg
• Primary or Secondary: Primary
• Content And Storage: 2°C to 8°C
• Isotype: IgG2a

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
• Clone: PAb416
• Formulation: In 50mM sodium phosphate buffer, 0.2% gelatin, pH 7.5.
• Immunogen: purified SV40 large T-antigen
• Regulatory Status: RUO
• Test Specificity: Recognizes ∽94kDa SV40 large T antigen in SV80 and SV-T2 cells.
• Form: Purified

For Research Use Only