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TCP-1 beta Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA522221

Catalog No. PIPA522221


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Description

Description

PA5-22221 targets TCP-1 beta in IHC (P) and WB applications and shows reactivity with Human and mouse samples. The PA5-22221 immunogen is a recombit fragment corresponding to a region within amino acids 277 and 503 of TCP1 beta (Uniprot IDNo.P78371). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

TCP-1 beta is a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). The CCT complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the TCP-1 beta gene have been observed but not thoroughly characterized. A disease associated with TCP-1 beta protein dysfunction include epididymo-orchitis.
Specifications

Specifications

TCP-1 beta
Polyclonal
Unconjugated
CCT2
Liquid
CCT2
Recombit fragment corresponding to a region within amino acids 277 and 503 of TCP1 beta (Uniprot IDNo.P78371)
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
P78371, P80314
99D8.1, CCT-beta, CCTB, PRO1633, TCP-1-beta, T-complex protein 1 subunit beta, T-complex protein 1, beta subunit, chaperonin containing t-complex polypeptide 1, beta subunit, chaperonin containing t-complex polypeptide 1, subunit 2
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
10576, 12461
Documents
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