TCP-1 beta Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA522221

Catalog No. PIPA522221

Description

PA5-22221 targets TCP-1 beta in IHC (P) and WB applications and shows reactivity with Human and mouse samples. The PA5-22221 immunogen is a recombit fragment corresponding to a region within amino acids 277 and 503 of TCP1 beta (Uniprot IDNo.P78371). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

TCP-1 beta is a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). The CCT complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the TCP-1 beta gene have been observed but not thoroughly characterized. A disease associated with TCP-1 beta protein dysfunction include epididymo-orchitis.

Specifications

• Antigen: TCP-1 beta
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCT2
• Format: Liquid
• Gene Symbols: CCT2
• Immunogen: Recombit fragment corresponding to a region within amino acids 277 and 503 of TCP1 beta (Uniprot IDNo.P78371)
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human, Mouse

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P78371, P80314
• Gene Alias: 99D8.1, CCT-beta, CCTB, PRO1633, TCP-1-beta, T-complex protein 1 subunit beta, T-complex protein 1, beta subunit, chaperonin containing t-complex polypeptide 1, beta subunit, chaperonin containing t-complex polypeptide 1, subunit 2
• Host Species: Rabbit
• Isotype: IgG
• Quantity: 100 μL
• Storage Requirements: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Primary or Secondary: Primary
• Gene ID (Entrez): 10576, 12461