TCP-1 theta Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA521689
This antibody targets TCP-1 theta in IHC (P) and WB applications and shows reactivity with Human and mouse samples. The PA5-21689 immunogen is a recombit fragment corresponding to a region within amino acids 111 and 367 of TCP1 theta (Uniprot IDNo.P50990). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.TCP-1 theta is theta subunit of the CCT (chaperonin containing TCP1 complex) chaperonin molecule which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of the newly synthesized proteins. Molecular chaperones assist in the protein folding upon ATP hydrolysis and TCP-1 theta may play a role in the assembly of the BBsome, a complex that is involved in ciliogenesis regulating transport vesicles to the cilia. Further, TCP-1 theta is also involved in the folding of actin and tubulin. The intact CCT complex is composed of eight polypeptides in a double ring structure. CCT is important within cells in the folding of the VHL tumor suppressor protein.
|Recombit fragment corresponding to a region within amino acids 111 and 367 of TCP1 theta (Uniprot IDNo.P50990)|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7|
|C21orf112, Cctq, D21S246, PRED71, CCT-theta, T-complex protein 1 subunit theta, T-complex protein 1, theta subunit, TCP-1-theta, renal carcinoma antigen NY-REN-15|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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