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TCR β Chain Hamster anti-Mouse, PE-Cy7, Clone: H57-597, BD

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BDB560729 50 μg
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Catalog No. BDB560729 Supplier BD Biosciences Supplier No. 560729
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Description

Hamster Monoclonal Antibody

The H57-597 antibody reacts with a common epitope of the β chain of the T-cell Receptor (TCR) complex on αβ TCR-expressing thymocytes and peripheral T lymphocytes and NK1.1+ thymocytes and NK-T cells of all mouse strains tested. It does not react with γδ TCR-bearing T cells. In the fetal and adult thymus, the TCR β-chain may form homodimers or pair with the pre-TCR α-chain on the surface of immature thymocytes before expression of the TCR α-chain. Plate-bound or soluble H57-597 antibody activates αβ TCR-bearing T cells, and plate-bound mAb can induce apoptotic death.

Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen TCR β Chain
Applications Flow Cytometry
Classification Monoclonal
Clone H57-597
Concentration 0.2mg/mL
Conjugate PE-Cyanine7
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Hamster
Immunogen TCR affinity-purified from mouse T-cell hybridoma DO-11.10
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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