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TMEM184C Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520933

Catalog No. PIPA520933


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Description

Description

A suggested positive control is mouse heart tissue lysate. PA5-20933 can be used with blocking peptide PEP-1047.

Anaplastic thyroid cancer is one of the most lethal forms of cancer, but the precise carcinogenic mechanism has not been identified. TMEM184C, also known as TMEM34, was identified in a cDNA microarray analysis as being down-regulated in anaplastic thyroid cancers compared to normal thyroid tissues. TMEM184C protein expression was also lower in cell lines derived from these types of cancers compared to that of normal thyroid tissues or cell lines based on other types of thyroid cancers. Furthermore, transfection of TMEM34 into KTA2 cells led to the inhibition of cell growth, suggesting that TMEM184C might act as a tumor suppressor in anaplastic thyroid cancers.
Specifications

Specifications

TMEM184C
Polyclonal
Unconjugated
TMEM184C
Liquid
TMEM184C
A 15 amino acid peptide near the carboxy terminus of human TMEM184C.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9NVA4, Q3TPR7, Q810F5
PRO1355, TMEM34; transmembrane protein 34
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
234463, 291946, 55751
Documents
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