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Invitrogen™ TMEM184C Polyclonal Antibody
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Catalog No. PIPA520933
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100 μg
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Catalog No. Quantity
PIPA520933 100 μg
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Catalog No. PIPA520933 Supplier Invitrogen™ Supplier No. PA520933
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Description

Rabbit Polyclonal Antibody

A suggested positive control is mouse heart tissue lysate. PA5-20933 can be used with blocking peptide PEP-1047.

Anaplastic thyroid cancer is one of the most lethal forms of cancer, but the precise carcinogenic mechanism has not been identified. TMEM184C, also known as TMEM34, was identified in a cDNA microarray analysis as being down-regulated in anaplastic thyroid cancers compared to normal thyroid tissues. TMEM184C protein expression was also lower in cell lines derived from these types of cancers compared to that of normal thyroid tissues or cell lines based on other types of thyroid cancers. Furthermore, transfection of TMEM34 into KTA2 cells led to the inhibition of cell growth, suggesting that TMEM184C might act as a tumor suppressor in anaplastic thyroid cancers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TMEM184C
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene TMEM184C
Gene Accession No. Q3TPR7, Q810F5, Q9NVA4
Gene Alias 8430433H16Rik; AI645453; AL033298; BC004056; DNA sequence AY228474; PRO1355; TMEM184C; Tmem34; Transmembrane protein 184C; transmembrane protein 34
Gene Symbols TMEM184C
Host Species Rabbit
Immunogen A 15 amino acid peptide near the carboxy terminus of human TMEM184C.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 234463, 291946, 55751
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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