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Apexbio Technology LLC Anti-TNFRSF10B/TRAILR2/CD262 Antibody (Tigatuzumab) 1mg

Supplier: Apexbio Technology LLC F10441

Tigatuzumab (CAS 918127-53-4) is a recombinant human IgG1 monoclonal antibody targeting tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) also known as TRAIL receptor 2 (TRAILR2) or CD262 It is designed to bind DR5 a receptor expressed on the surface of diverse cancer cells thereby modulating apoptosis-associated signaling pathways Tigatuzumab exerts its biological activity primarily through induction of apoptosis via receptor-mediated caspase-dependent mechanisms leading to tumor cell death and inhibition of tumor growth Based on these pharmacological properties tigatuzumab holds research potential in oncology and apoptosis-associated signaling pathway studies both in vitro and in vivo
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