TOB2 Rabbit anti-Bovine, Canine, Chicken, Equine, Human, Mouse, Non-human primate, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523289
DescriptionTOB2 is a 344 amino acid rich novel member of the Tob/BTG1 anti-proliferative family of proteins characterized by similarities in their N-terminal BTG/Tob homology domains. This anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases and is involved in cell cycle regulation through interaction with Caf1, a component of the CCR4 transcription factor complex that associates with cyclin-dependent kinases. Recent reports suggest that TOB2 plays important roles in spermatogenesis, embryonic dorsoventral patterning, osteogenesis, T-cell activation, learning and memory and acts primarily as a transcriptional repressor in several signaling pathways. TOB2, a signaling protein, may participate in transcriptional regulation of several genes. It is a regulatory protein ubiquitously expressed in most of the tissues.
|Synthetic peptide (74 RSGLAVEDVRANVPEELS 91) of TOB2 protein.|
|Bovine, Canine, Chicken, Equine, Human, Mouse, Non-human primate|
|PBS with 0.05% BSA and 0.05% sodium azide|
|TOB4, TOBL, TROB2, protein Tob2, protein Tob4, transducer of erbB-2 2|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|100055713, 10766, 417992, 481233, 507934, 57259|
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