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TXNIP Rabbit anti-Human, Non-human primate, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523485

Catalog No. PIPA523485


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Description

Description

Thioredoxin-interacting protein belongs to the arrestin family. It acts as an oxidative stress mediator by inhibiting thioredoxin activity or by inhibiting thioredoxin activity or by limiting its bioavailability. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells. Recently reported, TXNIP deficiency led to the impairment of NLRP3 inflammasome activation to innate immune responses and reduced secretion of interleukin IL-1ß.
Specifications

Specifications

TxNIP
Polyclonal
Unconjugated
TXNIP
Liquid
TXNIP
Synthetic peptide (125 VKAFLDRPSQPTQETKKN 142) of TxNIP protein.
Protein A
RUO
Antibody
Polyclonal
Human, Non-human Primate
Western Blot
1 mg/mL
PBS with 0.05% sodium azide
Q8BG60, Q9H3M7
EST01027, HHCPA78, THIF, VDUP1, thioredoxin binding protein 2, thioredoxin-binding protein 2, thioredoxin-interacting protein, upregulated by 1,25-dihydroxyvitamin D-3, vitamin D3 up-regulated protein 1
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
10628, 56338
Documents
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