anti-TYMS Matched Antibody Pair, Abnova

Supplier:  Abnova Corporation H00007298AP21

Catalog No. 89-017-369

Includes: Rabbit MaxPab™ affinity purified polyclonal anti-TYMS (100μg); Mouse purified polyclonal anti-TYMS (20μg); Sufficient for at least 3-5 x 96 well plates using recommended protocols.

Description

Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occurring antisense transcript rTSα (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase.

ELISA

Specifications

• Antigen: TYMS
• Classification: Monoclonal/Polyclonal
• Description: This antibody pair set comes with matched antibody pair to detect and quantify protein level of human TYMS.
• Gene Alias: HsT422/MGC88736/TMS/TS/TSase
• Host Species: Mouse, Rabbit
• Quantity: 1 Set
• Primary or Secondary: Primary
• Includes: Antibody pair set content: 1. Capture antibody: rabbit MaxPab™ affinity purified polyclonal anti-TYMS (100 μg) 2. Detection antibody: mouse purified polyclonal anti-TYMS (20 μg) *Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.
• Content And Storage: Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.

• Applications: ELISA
• Conjugate: Unconjugated
• Gene: TYMS
• Gene Symbols: TYMS
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 7298
• Target Species: Human