ZMIZ1 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA521133
A suggested positive control is K562 cell lysate. PA5-21133 can be used with blocking peptide PEP-1247.ZIMP10, also known as ZMIZ1, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein initially identified as a transcriptional co-activator of the androgen receptor (AR). ZIMP10 and the related protein ZIMP7 interact with PIAS3 and enhances AR-mediated transcription. Later experiments showed that ZIMP10 is also a co-activator of the p53 tumor suppressor. Mice deficient in ZIMP10 result in embryonic lethality by E10.5; these embryos reveal severe defects in the reorganization of the yolk sac vascular plexus, indicating that ZIMP10 plays an important role in proper vascular development.
|A 15 amino acid peptide near the amino terminus of human ZIMP10.|
|Antigen affinity chromatography|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 0.02% sodium azide|
|RP11-519K18.1, MIZ, RAI17, TRAFIP10, ZIMP10, hZIMP10; FLJ00092 protein; RP11-519K18.1; retinoic acid induced 17; zinc finger MIZ domain-containing protein 1; zinc finger-containing, Miz1, PIAS-like protein on chromosome 10|
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
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