Cayman Chemical ANTIBODY 4-IPP 10mg

Supplier:  Cayman Chemical 3177010 MG

An adenosine A3 receptor agonist binds selectively to adenosine A3 receptors (Ki 0 33 nM) over A1 and A2A receptors (Kis 820 and 470 nM respectively) and inhibits adenylate cyclase activity (IC50 66 8 nM) inhibits proliferation of B16/F10 melanoma cells and increases proliferation of murine bone marrow cells in vitro at 10 and 100 nM induces accumulation of cells in the G0/G1 phase of the cell cycle and induces apoptosis at 100 nM prevents the development of lung metastatic foci in a B16/F10 mouse model of lung metastasis and reverses decreases in the number of white blood cells and neutrophils induced by cyclophosphamide at 6 Ug/kg

Catalog No. 50-299-0884