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Cayman Chemical ANTIBODY 5S 6R-EET 50UG

Supplier: Cayman Chemical 900434950 UG
A naphthoquinone that has diverse biological activities inhibits a panel of 10 CYPs (IC50s 1.4-4.0 UM) cytotoxic to H1975 A549 PC-9 and H460 NSCLC cells (IC50s 3.9 4.7 20.7 and 17.3 UM respectively) inhibits the migration of as well as reduces EGFR and STAT3 signaling and induces apoptosis in H1975 PC-9 and H460 cells at 0.5 1 and 2 UM reduces tumor weight and intratumoral STAT3 phosphorylation in an H1975 mouse xenograft model at 1 mg/kg inhibits SARS-CoV-2 PLpro (IC50 5.05 UM) reduces BALF levels of Tnf-a Il-1a and Il-6 in a mouse model of acute lung injury induced by poly (IC) and SARS-CoV-2 spike glycoprotein at 300 mg/kg
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