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Cayman Chemical ANTIBODY AZ-GHS-22 1mg

Supplier: Cayman Chemical 346111 MG
A histamine H2 receptor antagonist with gastroprotective activity inhibits histamine-induced cAMP production in CHO cells expressing human histamine H2 receptors at 10 nM reduces hemorrhagic esophageal lesion size and gastric acid secretion in a rat model of pyloric ligation-induced reflux esophagitis at 3 10 and 30 mg/kg prevents 5-fluorouracil-induced intestinal mucositis diarrhea and body weight loss in wild-type but not Trpv1-/- or sensory deafferented mice from 3-30 mg/kg reduces indomethacin-induced antral ulcer size in wild-type but not chemically-deafferented rats at 10 mg/kg
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