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Cayman Chemical ANTIBODY G150 1mg
SDP

Supplier:  Cayman Chemical 283181 MG

Encompass_Preferred

An inhibitor of topoisomerase I that inhibits topoisomerase I-mediated DNA cleavage 10-fold more potently than topotecan inhibits the growth of and is cytotoxic to human and mouse bone marrow cells in vitro (IC50s 0 4 and 2 3 nM respectively IC90s 1 2 and 8 4 nM respectively) inhibits the growth of and is cytotoxic to human tumor cell lines in vitro (IC50s 0 15-2 nM IC90s 0 7-8 3 nM) inhibits tumor growth in mouse xenograft models (1 36-2 7 mg/kg)

Catalog No. 50-294-0213


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